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Article

Role of the MRP1/ABCC1 Multidrug Transporter Protein in Cancer

1 Jan 2007

Abstract excerpt

Multidrug resistance is a major obstacle to cancer treatment and leads to poor prognosis for the patient. Multidrug resistance-associated protein 1 (MRP1) transports a wide range of therapeutic agents as well as diverse physiological substrates and may play a role in the development of drug resistance in several cancers including those of the lung, breast and prostate, as well as childhood neuroblastoma. The...

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PMID: 18085475
DOI: 10.1080/15216540701736285

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