Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of High-Level <i>MRP1</i> Expression With Poor Clinical Outcome in a Large Prospective Study of Primary Neuroblastoma

31 Mar 2006

Abstract excerpt

PURPOSE: We have previously shown in a retrospective study that expression of the multidrug transporter gene MRP1 (ABCC1) is associated with outcome in neuroblastoma. We have now undertaken a prospective analysis to examine the independent prognostic significance of MRP1 expression in a large cohort of primary untreated neuroblastomas. PATIENTS AND METHODS: Two hundred nine diagnostic neuroblastoma samples from...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer, Hypoxia, and Metabolism
Share to Neuroblastoma Research and Treatments
Share to S100 Proteins and Annexins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 16575006
DOI: 10.1200/jco.2005.01.6196

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of High-Level <i>MRP1</i> Expression With Poor Clinical Outcome in a Large Prospective Study of Primary NeuroblastomaPMID 16575006Read ↗

Expression of the Gene for Multidrug-Resistance–Associated Protein and Outcome in Patients with NeuroblastomaSemantic proximity Read ↗

Expression of multidrug transporterMRP4/ABCC4is a marker of poor prognosis in neuroblastoma and confers resistance to irinotecanin vitroSemantic proximity Read ↗

Role of the MRP1/ABCC1 Multidrug Transporter Protein in CancerSemantic proximity Read ↗

ABCC4/MRP4: a MYCN-regulated transporter and potential therapeutic target in neuroblastomaSemantic proximity Read ↗

MYCN-mediated regulation of the MRP1 promoter in human neuroblastomaSemantic proximity Read ↗

Role of chemotherapy resistance genes in outcome of neuroblastomaSemantic proximity Read ↗

MRP1 gene expression level regulates the death and differentiation response of neuroblastoma cellsSemantic proximity Read ↗

Small-Molecule Multidrug Resistance–Associated Protein 1 Inhibitor Reversan Increases the Therapeutic Index of Chemotherapy in Mouse Models of NeuroblastomaSemantic proximity Read ↗

<i>MDR1</i> and <i>MRP1</i> gene expression are independent predictors for treatment outcome in adult acute myeloid leukaemiaSemantic proximity Read ↗

Alternative Splicing of the <b> <i>Multidrug Resistance Protein 1/ATP Binding Cassette Transporter Subfamily</i> </b> Gene in Ovarian Cancer Creates Functional Splice Variants and Is Associated with Increased Expression of the Splicing Factors PTB and SRp20Semantic proximity Read ↗

Expression of N-myc andMRP genes and their relationship to N-myc gene dosage and tumor formation in a murine neuroblastoma modelSemantic proximity Read ↗

Structural, mechanistic and clinical aspects of MRP1.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.