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ATP‐binding cassette (ABC) transporters in cancer: A review of recent updates

13 Aug 2021

Abstract excerpt

The ATP-binding cassette (ABC) transporter superfamily is one of the largest membrane protein families existing in wide spectrum of organisms from prokaryotes to human. ABC transporters are also known as efflux pumps because they mediate the cross-membrane transportation of various endo- and xenobiotic molecules energized by ATP hydrolysis. Therefore, ABC transporters have been considered closely to multidrug...

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PMID: 34388310
DOI: 10.1111/jebm.12434

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