Article
Relationship between polymorphism of DC-SIGN (CD209) gene and the susceptibility to pulmonary tuberculosis in an eastern Chinese population.
Human immunology - 1 Feb 2011
Zheng Ruijuan, Zhou Yan, Qin Lianhua, Jin Ruiliang, Wang Jie, Lu Junmei, Wang WeiBing, Tang Shenjie, Hu Zhongyi
Abstract excerpt
Dendritic cell-specific intracellular adhesion molecule-3-grabbing nonintegrin (DC-SIGN) is an important receptor for Mycobacterium tuberculosis on human dendritic cells. Previous studies have shown that the variation, especially the -871A/G and -336A/G in DC-SIGN promoter influenced the suscepti...
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