Article
Sequencing of DC-SIGN promoter indicates an association between promoter variation and risk of nasopharyngeal carcinoma in cantonese.
BMC medical genetics - 11 Nov 2010
Xu Ya-Fei, Liu Wan-Li, Dong Ju-Qin, Liu Wen-Sheng, Feng Qi-Sheng, Chen Li-Zhen, Zeng Yi-Xin, Zeng Mu-Sheng, Jia Wei-Hua
Abstract excerpt
BACKGROUND: The dendritic cell-specific intercellular adhesion molecule 3 grabbing non-integrin (DC-SIGN) is an important pathogen recognition receptor of the innate immune system. DC-SIGN promoter variants play important role in the susceptibility to various infectious diseases. Nasopharyngeal carcinoma (NPC) is a malignancy that is common in southern China and whether DC-SIGN promoter variants have effects on...
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