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Article

Drosophila Follistatin exhibits unique structural modifications and interacts with several TGF-beta family members.

Mechanisms of development - 1 Jan 2000

Bickel Daniela, Shah Ripal, Gesualdi Scott C, Haerry Theodor E

Abstract excerpt

Follistatin (FS) is one of several secreted proteins that modulate the activity of TGF-beta family members during development. The structural and functional analysis of Drosophila Follistatin (dFS) reveals important differences between dFS and its vertebrate orthologues: it is larger, more positively charged, and proteolytically processed. dFS primarily inhibits signaling of Drosophila Activin (dACT) but can also...

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Identifiers

PMID: 18077144
DOI: 10.1016/j.mod.2007.09.013
PMCID: PMC2278114

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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