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Article

Overexpression of Mouse Follistatin Causes Reproductive Defects in Transgenic Mice

1 Jan 1998

Abstract excerpt

Follistatin is an activin-binding protein that can act as an activin antagonist in vitro. Follistatin also binds heparin sulfate proteoglycans and may function as a reservoir for activins in vivo. In the mouse, follistatin mRNA is first detected in the deciduum on embryonic day 5.5 and later in the developing hindbrain, somites, vibrissae, teeth, epidermis, and muscle. We have previously shown that...

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PMID: 9440814
DOI: 10.1210/mend.12.1.0053

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