Article
Follistatin preferentially antagonizes activin rather than BMP signaling in Drosophila.
Genesis (New York, N.Y. : 2000) - 1 Apr 2009
Pentek Jozsef, Parker Louise, Wu Alison, Arora Kavita
Abstract excerpt
Ligands of the transforming growth factor-beta (TGF-beta) superfamily play important roles in embryonic patterning and development throughout the animal kingdom. Consequently, extracellular factors that affect ligand stability, mobility, and receptor interaction also have profound effects on development. One such regulator, Follistatin (Fst), functions as an inhibitor of both activin and bone morphogenetic...
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