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Article

Follistatin N terminus differentially regulates muscle size and fat in vivo.

Experimental & molecular medicine - 15 Sept 2017

Zheng Hui, Qiao Chunping, Tang Ruhang, Li Jianbin, Bulaklak Karen, Huang Zhenhua, Zhao Chunxia, Dai Yi, Li Juan, Xiao Xiao

Abstract excerpt

Delivery of follistatin (FST) represents a promising strategy for both muscular dystrophies and diabetes, as FST is a robust antagonist of myostatin and activin, which are critical regulators of skeletal muscle and adipose tissues. FST is a multi-domain protein, and deciphering the function of different domains will facilitate novel designs for FST-based therapy. Our study aims to investigate the role of the...

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Source

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Identifiers

PMID: 28912572
DOI: 10.1038/emm.2017.135
PMCID: PMC5628274

Genes

FST

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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