The Involvement of ERCC2/XPD and ERCC6/CSB Wild Type Alleles in Protection Against Aging and Cancer.

doi:10.2174/1874609810666170707101548

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Article

The Involvement of ERCC2/XPD and ERCC6/CSB Wild Type Alleles in Protection Against Aging and Cancer.

Current aging science - 1 Jan 2018

Savina Nataliya V, Nikitchenko Nataliya V, Kuzhir Tatyana D, Rolevich Alexander I, Krasny Sergei A, Goncharova Roza I

Abstract excerpt

BACKGROUND: DNA helicases maintain genome stability, and their deficiency is associated with disorders resembling premature aging as well as contributes to carcinogenesis. Their functions are determined by the respective genes encoding nucleotide excision repair initiating proteins, e.g. XPD and CSB. OBJECTIVE: The present study aimed to investigate the influence of genetic variations in ERCC2/XPD (rs1799793,...

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Identifiers

PMID: 28707579
DOI: 10.2174/1874609810666170707101548

Genes

ERCC2
ERCC6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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