Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

XPD/ERCC2 polymorphisms and risk of head and neck cancer: a case-control analysis.

Carcinogenesis - 1 Dec 2000

Sturgis E M, Zheng R, Li L, Castillo E J, Eicher S A, Chen M, Strom S S, Spitz M R, Wei Q

Abstract excerpt

DNA repair capacity is central in maintaining normal cellular functions. Variants of several DNA repair genes,including the nucleotide excision repair gene XPD, have been described recently. Because we previously reported that patients with squamous cell carcinoma of the head and neck (SCCHN) had lower DNA repair capacity than healthy controls, we hypothesized that inherited polymorphisms of XPD may contribute to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alcohol Drinking
Share to Carcinoma, Squamous Cell
Share to DNA Helicases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Head and Neck Neoplasms

Share to Homozygote

Share to Proteins

Share to Smoking

Share to Xeroderma Pigmentosum Group D Protein

Source

Identifiers

PMID: 11133811
DOI: 10.1093/carcin/21.12.2219

Genes

ERCC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

XPD/ERCC2 polymorphisms and risk of head and neck cancer: a case-control analysis.PMID 11133811Read ↗

DNA repair gene ERCC1 and ERCC2/XPD polymorphisms and risk of squamous cell carcinoma of the head and neck.Semantic proximity Read ↗

XPD/ERCC2 EXON 8 Polymorphisms: rarity and lack of significance in risk of squamous cell carcinoma of the head and neck.Semantic proximity Read ↗

Association between the XPD/ERCC2 Lys751Gln polymorphism and risk of cancer: evidence from 224 case-control studies.Semantic proximity Read ↗

XRCC1 and XPD genetic polymorphisms, smoking and breast cancer risk in a Finnish case-control study.Semantic proximity Read ↗

DNA repair genes XPC, XPD, XRCC1, and XRCC3 are associated with risk and survival of squamous cell carcinoma of the head and neck.Semantic proximity Read ↗

Polymorphisms in human DNA repair genes and head and neck squamous cell carcinoma.Semantic proximity Read ↗

Genetic polymorphisms in the nucleotide excision repair pathway and lung cancer risk: a meta-analysis.Semantic proximity Read ↗

ERCC2 /XPD gene polymorphisms and lung cancer: a HuGE review.Semantic proximity Read ↗

Polymorphisms in DNA damage response genes and head and neck cancer risk.Semantic proximity Read ↗

ERCC2/XPD gene polymorphisms and cancer risk.Semantic proximity Read ↗

Association of polymorphisms in the cyclin D1 and XPD genes and susceptibility to cancers of the upper aero-digestive tract.Semantic proximity Read ↗

Polymorphisms of DNA repair genes: ADPRT, XRCC1, and XPD and cancer risk in genetic epidemiology.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.