Article
DNA repair gene ERCC1 and ERCC2/XPD polymorphisms and risk of squamous cell carcinoma of the head and neck.
Archives of otolaryngology--head & neck surgery - 1 Sept 2002
Sturgis Erich M, Dahlstrom Kristina R, Spitz Margaret R, Wei Qingyi
Abstract excerpt
OBJECTIVE: To determine the effect of the ERCC1 C8092A polymorphism and the ERCC2/XPD G23591A polymorphism on the risk of squamous cell carcinoma of the head and neck (SCCHN). DESIGN: A hospital-based case-control study. SUBJECTS: A total of 330 newly diagnosed case subjects with SCCHN and 330 cancer-free control subjects matched on age (+/- 5 years), sex, smoking status, and alcohol use. All subjects were...
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