Article
Functional reconstruction and synthetic mimicry of a conformational epitope using CLIPS technology.
Journal of molecular recognition : JMR - 1 Jan 2000
Timmerman Peter, Puijk Wouter C, Meloen Rob H
Abstract excerpt
This paper describes immunization studies with CLIPS-constrained peptides covering only the major part (beta3-loop) of a structurally complex antigenic site on human Follicle Stimulating Hormone beta-subunit (FSH-beta). In cases where linear and SS-constrained peptides fail, the CLIPS-constrained...
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