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Article

Evaluation of subunit truncation and the nature of the spacer for single chain human gonadotropins.

European journal of biochemistry - 1 May 1997

Heikoop J C, van Beuningen-de Vaan M M, van den Boogaart P, Grootenhuis P D

Abstract excerpt

Three single chain gonadotropins were designed based on the three-dimensional-structure of human choriogonadotropin and structure/activity relationships of the glycoprotein hormones. In each single chain, the C-terminal end of the human choriogonadotropin beta subunit is connected via Ser-Gly repeats to the N-terminal end of the alpha subunit. In addition, two of the single chains have truncated subunits. The...

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Identifiers

PMID: 9183002
DOI: 10.1111/j.1432-1033.1997.00656.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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