Article
Identification of amino acids in the C-terminal region of human follicle-stimulating hormone (FSH) beta-subunit involved in binding to human FSH receptor.
Endocrinology - 1 Sept 1994
Lindau-Shepard B, Roth K E, Dias J A
Abstract excerpt
Recent analyses of human FSH (hFSH) using antipeptide antibodies, monoclonal antibodies, and chimeric constructions of hCG/hFSH strongly suggest that the C-terminal region, including residues 81-100 of the hFSH beta-subunit, is involved in subunit association as well as hFSH heterodimer binding a...
Topics
- Amino Acid Sequence
- Amino Acids
- Animals
- Base Sequence
- Cell Line
- Enzyme-Linked Immunosorbent Assay
- Follicle Stimulating Hormone
- Humans
- Insecta
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Mutation