The flanking amino acids of the human follitropin beta-subunit 33-53 region are involved in assembly of the follitropin heterodimer.

doi:10.1210/endo.132.6.8504759

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Article

The flanking amino acids of the human follitropin beta-subunit 33-53 region are involved in assembly of the follitropin heterodimer.

Endocrinology - 1 Jun 1993

Roth K E, Liu C, Shepard B A, Shaffer J B, Dias J A

Abstract excerpt

Previous analyses of the topology of human follitropin (hFSH) with monoclonal antibodies and antipeptide antibodies have led to a current operating hypothesis that some amino acids within the hFSH beta 33-53 region are surface oriented, and others participate in subunit contact. Protein structura...

Topics

Amino Acid Sequence
Animals
Base Sequence
Cell Line
Follicle Stimulating Hormone
Humans
Molecular Sequence Data
Mutagenesis, Site-Directed
Mutation
Oligonucleotide Probes
Protein Folding
Recombinant Proteins

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