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Protein and gene expression of tumour necrosis factor receptors I and II and their promoter gene polymorphisms in Alzheimer's disease.

Experimental gerontology - 1 Jun 2007

Culpan Doris, Cornish Abigail, Love Seth, Kehoe Patrick G, Wilcock Gordon K

Abstract excerpt

The levels of pro-inflammatory cytokines, such as tumour necrosis factor-alpha (TNF-alpha), are increased in the brain in Alzheimer's disease (AD). Most of the biological properties of TNF-alpha are mediated through its two receptors, tumour necrosis factor receptors I and II (TNF-RI and TNF-RII). We have used immunohistochemistry, Western blotting and real time-PCR (RT-PCR) on frontal (BA 6/24) and temporal (BA...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17267158
DOI: 10.1016/j.exger.2006.12.001

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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