Article
IL4 in the 5q31 context: association studies of type 1 diabetes and rheumatoid arthritis in the Spanish population.
Immunogenetics - 1 Jan 2008
Nuñez Concepción, Santiago Jose Luis, Varadé Jezabel, de la Calle Hermenegildo, Figueredo M Angeles, Fernandez-Gutierrez Benjamín, de la Concha Emilio G, Urcelay Elena, Martínez Alfonso
Abstract excerpt
IL4, the gene coding the prototypic Th2 cytokine, has been frequently studied in the context of several inflammatory conditions, but conclusive results have not been obtained. This gene is located in the 5q31-33 complex genetic region, which shows some susceptibility factors to type 1 diabetes (T1D) and rheumatoid arthritis (RA) among other inflammatory conditions. Our aim was to assess the involvement on T1D and...
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