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Article

Polymorphic variant at the IL2 region is associated with type 1 diabetes and may affect serum levels of interleukin-2.

Molecular biology reports - 1 Dec 2013

Fichna Marta, Zurawek Magdalena, Fichna Piotr, Ziółkowska-Suchanek Iwona, Januszkiewicz Danuta, Nowak Jerzy

Abstract excerpt

Polymorphic variants at the interleukin-2 (IL2) locus affect the risk of several autoimmune disorders. Our aim was to evaluate the association of the four IL2 polymorphisms (rs6822844, rs6534349, rs2069762 and rs3136534) with type 1 diabetes (T1D) in the Polish population, and to correlate them with the serum interleukin-2 levels. 543 unrelated T1D patients and 706 healthy control subjects were enrolled. The...

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Identifiers

PMID: 24154763
DOI: 10.1007/s11033-013-2815-9
PMCID: PMC3835945

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