Article
Binding of Escherichia coli initiation factor IF2 to 30S ribosomal subunits: a functional role for the N-terminus of the factor.
Biochemical and biophysical research communications - 18 Nov 1998
Moreno J M, Kildsgaard J, Siwanowicz I, Mortensen K K, Sperling-Petersen H U
Abstract excerpt
In the initiation step of bacterial protein synthesis initiation factor IF2 has to join the 30S ribosomal subunit in order to promote the binding of the fMet-tRNAMetf. In order to identify regions within IF2 which may be involved in the primary ribosome-factor interaction, we have constructed sev...
Topics
- Amino Acid Sequence
- Animals
- Antibodies, Monoclonal
- Binding Sites
- Escherichia coli
- Molecular Sequence Data
- Mutation
- Peptide Fragments
- Peptide Initiation Factors
- Prokaryotic Initiation Factor-2
- Ribosomal Proteins