Article
Binding of Escherichia coli initiation factor IF2 to 30S ribosomal subunits: a functional role for the N-terminus of the factor.
Biochemical and biophysical research communications - 18 Nov 1998
Moreno J M, Kildsgaard J, Siwanowicz I, Mortensen K K, Sperling-Petersen H U
Abstract excerpt
In the initiation step of bacterial protein synthesis initiation factor IF2 has to join the 30S ribosomal subunit in order to promote the binding of the fMet-tRNAMetf. In order to identify regions within IF2 which may be involved in the primary ribosome-factor interaction, we have constructed several C-terminal and N-terminal truncated forms of the factor as well as isolated structural domains, and tested them in...
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