Article
The role of Slit-Robo signaling in the generation, migration and morphological differentiation of cortical interneurons.
Developmental biology - 15 Jan 2008
Andrews William, Barber Melissa, Hernadez-Miranda Luis R, Xian Jian, Rakic Sonja, Sundaresan Vasi, Rabbitts Terence H, Pannell Richard, Rabbitts Pamela, Thompson Hannah, Erskine Lynda, Murakami Fujio, Parnavelas John G
Abstract excerpt
Cortical interneurons in rodents are generated in the ventral telencephalon and migrate tangentially into the cortex. This process requires the coordinated action of many intrinsic and extrinsic factors. Here we show that Robo1 and Robo2 receptor proteins are dynamically expressed throughout the period of corticogenesis and colocalize with interneuronal markers, suggesting that they play a role in the migration...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.