Article

RalGAPα1is dispensable for embryonic cortical morphogenesisin mice

2021-04-16

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Cortical morphogenesis is a complex process and involves a large number of genes. RalGAPα1 gene (also called Tulip1 ), mapped to chromosome 14q13.2, is a candidate gene for the 14q13 deletion syndrome associated with delayed brain development. However, it remains unknown whether RalGAPα1 directly regulates cortical development. <bold>Methods:</bold> To address t...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 7544cf93-d225-531f-a8ad-f3a575125f80
DOI: 10.21203/rs.3.rs-408297/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

RalGAPα1is dispensable for embryonic cortical morphogenesisin miceDOI 10.21203/rs.3.rs-408297/v1Read

Morphological and functional aspects of progenitors perturbed in cortical malformationsSemantic proximity Read

Cellular resolution anatomical and molecular atlases for prenatal human brainsSemantic proximity Read

A kinase-independent function of cyclin-dependent kinase 6 promotes outer radial glia expansion and neocortical foldingSemantic proximity Read

Impaired cortical neurogenesis in plexin-B1 and -B2 double deletion mutant.Semantic proximity Read

Human disorders of cortical development: from past to present.Semantic proximity Read

<i>MIR3607</i> regulates cerebral cortex development via activation of Wnt/βCat signalingSemantic proximity Read

Evolution of Cerebral Cortical DevelopmentSemantic proximity Read

The role of Slit-Robo signaling in the generation, migration and morphological differentiation of cortical interneurons.Semantic proximity Read

ERK signaling integrates multiple mechanisms to drive cortical evolutionary expansionSemantic proximity Read

Foxg1 suppresses early cortical cell fate.Semantic proximity Read

Dorsal telencephalon‐specific <i>RA‐GEF‐1</i> knockout mice develop heterotopic cortical mass and commissural fiber defectSemantic proximity Read

Vertical transmission of Zika virus targeting the radial glial cells affects cortex development of offspring miceSemantic proximity Read