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Article

A genome-wide search for susceptibility genes in human systemic lupus erythematosus sib-pair families.

Proceedings of the National Academy of Sciences of the United States of America - 8 Dec 1998

Gaffney P M, Kearns G M, Shark K B, Ortmann W A, Selby S A, Malmgren M L, Rohlf K E, Ockenden T C, Messner R P, King R A, Rich S S, Behrens T W

Abstract excerpt

Systemic lupus erythematosus (SLE) is an autoimmune multisystem inflammatory disease characterized by the production of pathogenic autoantibodies. Previous genetic studies have suggested associations with HLA Class II alleles, complement gene deficiencies, and Fc receptor polymorphisms; however,...

Topics

Adult
Female
Genetic Linkage
Genetic Predisposition to Disease
Genome, Human
HLA Antigens
Humans
Lupus Erythematosus, Systemic
Male
Middle Aged
Nuclear Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 9843983
DOI: 10.1073/pnas.95.25.14875
PMCID: PMC24543

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9843983-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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