Article
Induction of human immunodeficiency virus (HIV-1) envelope specific cell-mediated immunity by a non-homologous synthetic peptide.
PloS one - 28 Nov 2007
Achour Ammar, Biquard Jean-Michel, Krsmanovic Velibor, M'bika Jean-Pierre, Ficheux Damien, Sikorska Marianna, Cozzone Alain J
Abstract excerpt
BACKGROUND: Cell mediated immunity, including efficient CTL response, is required to prevent HIV-1 from cell-to-cell transmission. In previous investigations, we have shown that B1 peptide derived by Fourier transformation of HIV-1 primary structures and sharing no sequence homology with the parent proteins was able to generate antiserum which recognizes envelope and Tat proteins. Here we have investigated...
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