Article
Identification of multiple HIV-1 cytotoxic T-cell epitopes presented by human leukocyte antigen B35 molecules.
AIDS (London, England) - 1 Sept 1996
Shiga H, Shioda T, Tomiyama H, Takamiya Y, Oka S, Kimura S, Yamaguchi Y, Gojoubori T, Rammensee H G, Miwa K, Takiguchi M
Abstract excerpt
OBJECTIVE: To identify HIV-1 cytotoxic T lymphocyte (CTL) epitopes presented by human leukocyte antigen (HLA)-B35 molecules that are associated with the accelerated progression of AIDS using a reverse immunogenetic approach. METHODS: 8-mer to 11-mer sequences carrying two anchor residues at posit...
Topics
- Antigen Presentation
- Cytotoxicity, Immunologic
- Epitopes
- HIV-1
- HLA-B Antigens
- HLA-B35 Antigen
- HLA-B51 Antigen
- Humans
- Mutation
- Oligopeptides
- Protein Binding
- Recombinant Proteins
- T-Lymphocytes
- Vaccinia virus
