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Article

Cytotoxic T lymphocytes specific for HIV-1 gp160 antigen and synthetic P18IIIB peptide in an HLA-A11-immunized individual.

AIDS research and human retroviruses - 1 Jan 1994

Achour A, Lemhammedi S, Picard O, M'Bika J P, Zagury J F, Moukrim Z, Willer A, Beix F, Burny A, Zagury D

Abstract excerpt

Cytotoxic T cell determinants should be an important component of an anti-human immunodeficiency virus (HIV) vaccine. The epitopes of proteins can be defined with short synthetic peptides for class I-restricted CTLs. An immunodominant CTL epitope from the HIV-1 IIIB envelope protein gp160 comprising 15 amino acids (residues 315-329: RIQRGPGRAFVTIGK) (P18IIIB) has been identified that is recognized by class I MHC...

Topics

Amino Acid Sequence
Cell Line
Gene Products, env
HIV Envelope Protein gp160
HIV-1
HLA-A Antigens
HLA-A11 Antigen
Humans
Molecular Sequence Data
Peptide Fragments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

Protein Precursors

T-Lymphocytes, Cytotoxic

Vaccination

Source

Identifiers

PMID: 8179960
DOI: 10.1089/aid.1994.10.19

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8179960-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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