Definition of an immunodominant T cell epitope contained in the envelope gp41 sequence of HIV-1.

doi:10.1111/j.1365-2249.1992.tb06410.x

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Article

Definition of an immunodominant T cell epitope contained in the envelope gp41 sequence of HIV-1.

Clinical and experimental immunology - 1 Jan 1992

Bell S J, Cooper D A, Kemp B E, Doherty R R, Penny R

Abstract excerpt

The majority of the immunodominant amino acid sequences of HIV-1 that have been characterized to date are coded for by hypervariable gene sequences. These variable sequences are however interspersed with sequences that are highly conserved between HIV strains. Immunogenic viral products with amin...

Topics

Amino Acid Sequence
B-Lymphocytes
Epitopes
HIV Core Protein p24
HIV Envelope Protein gp41
HIV-1
Humans
Lymphocyte Activation
Molecular Sequence Data
Peptide Fragments
Phenotype
T-Lymphocytes

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