Article
Definition of an immunodominant T cell epitope contained in the envelope gp41 sequence of HIV-1.
Clinical and experimental immunology - 1 Jan 1992
Bell S J, Cooper D A, Kemp B E, Doherty R R, Penny R
Abstract excerpt
The majority of the immunodominant amino acid sequences of HIV-1 that have been characterized to date are coded for by hypervariable gene sequences. These variable sequences are however interspersed with sequences that are highly conserved between HIV strains. Immunogenic viral products with amino acid sequences that vary minimally between strains, and that consistently elicit both humoral and cellular immune...
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