Article
Short communication: HIV-1 Nef protein carries multiple epitopes suitable for induction of cellular immunity for an HIV vaccine in Africa.
AIDS research and human retroviruses - 1 Nov 2014
Kilpeläinen Athina, Axelsson Robertson Rebecca, Leitner Thomas, Sandström Eric, Maeurer Markus, Wahren Britta
Abstract excerpt
Using the early protein HIV Nef, new HLA class I binding epitopes of importance for immune responses to HIV were predicted for common African alleles. In total we identified 45 epitopes previously not described for the HLA alleles A*30:01, A*30:02, B*58:01, and C*07:01 and compared them to reported epitopes, primarily from HLA-A*02:01, from the Los Alamos database and our own vaccine studies. Related to its small...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.