Identification of naturally processed viral nonapeptides allows their quantification in infected cells and suggests an allele-specific T cell epitope forecast.

doi:10.1084/jem.174.2.425

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Article

Identification of naturally processed viral nonapeptides allows their quantification in infected cells and suggests an allele-specific T cell epitope forecast.

The Journal of experimental medicine - 1 Aug 1991

Falk K, Rötzschke O, Deres K, Metzger J, Jung G, Rammensee H G

Abstract excerpt

Virus-specific cytotoxic T lymphocytes (CTL) recognize virus-derived peptides presented by major histocompatibility complex (MHC) class I molecules on virus-infected cells. Such peptides have been isolated from infected cells and were compared to synthetic peptides. We found previously the Kd- or Db-restricted natural influenza nucleoprotein peptides to coelute on reversed phase high performance liquid...

Topics

Alleles
Amino Acid Sequence
Animals
Antigen-Presenting Cells
Chick Embryo
Chromatography, High Pressure Liquid
Epitopes
H-2 Antigens
Influenza A virus
Mice
Mice, Inbred C57BL

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Nucleocapsid Proteins

Nucleoproteins

Oligopeptides

RNA-Binding Proteins

T-Lymphocytes, Cytotoxic

Tumor Cells, Cultured

Source

Open in PubMed Open full text

Identifiers

PMID: 1713253
DOI: 10.1084/jem.174.2.425
PMCID: PMC2118916

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1713253-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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