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Article

NHK-1 phosphorylates BAF to allow karyosome formation in the Drosophila oocyte nucleus.

The Journal of cell biology - 3 Dec 2007

Lancaster Oscar M, Cullen C Fiona, Ohkura Hiroyuki

Abstract excerpt

Accurate chromosome segregation in meiosis requires dynamic changes in chromatin organization. In Drosophila melanogaster, upon completion of recombination, meiotic chromosomes form a single, compact cluster called the karyosome in an enlarged oocyte nucleus. This clustering is also found in humans; however, the mechanisms underlying karyosome formation are not understood. In this study, we report that...

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Identifiers

PMID: 18039935
DOI: 10.1083/jcb.200706067
PMCID: PMC2099182

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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