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Article

Caenorhabditis elegans BAF-1 and its kinase VRK-1 participate directly in post-mitotic nuclear envelope assembly.

The EMBO journal - 10 Jan 2007

Gorjánácz Mátyás, Klerkx Elke P F, Galy Vincent, Santarella Rachel, López-Iglesias Carmen, Askjaer Peter, Mattaj Iain W

Abstract excerpt

Barrier-to-autointegration factor (BAF) is an essential, highly conserved, metazoan protein. BAF interacts with LEM (LAP2, emerin, MAN1) domain-carrying proteins of the inner nuclear membrane. We analyzed the in vivo function of BAF in Caenorhabditis elegans embryos using both RNA interference and a temperature-sensitive baf-1 gene mutation and found that BAF is directly involved in nuclear envelope (NE)...

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Identifiers

PMID: 17170708
DOI: 10.1038/sj.emboj.7601470
PMCID: PMC1782363

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