Article
A histone code in meiosis: the histone kinase, NHK-1, is required for proper chromosomal architecture in Drosophila oocytes.
Genes & development - 1 Nov 2005
Ivanovska Irena, Khandan Tulasi, Ito Takashi, Orr-Weaver Terry L
Abstract excerpt
To promote faithful propagation of the genetic material during sexual reproduction, meiotic chromosomes undergo specialized morphological changes that ensure accurate segregation of homologous chromosomes. The molecular mechanisms that establish the meiotic chromosomal structures are largely unknown. We describe a mutation in a recently identified Histone H2A kinase, nhk-1, in Drosophila that leads to female...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
