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Article

Multiple Requirements of PLK1 during Mouse Oocyte Maturation

6 Feb 2015

Abstract excerpt

Polo-like kinase 1 (PLK1) orchestrates multiple events of cell division. Although PLK1 function has been intensively studied in centriole-containing and rapidly cycling somatic cells, much less is known about its function in the meiotic divisions of mammalian oocytes, which arrest for a long period of time in prophase before meiotic resumption and lack centrioles for spindle assembly. Here, using specific small...

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PMID: 25658810
DOI: 10.1371/journal.pone.0116783

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