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Article

Recruitment of BAF to the nuclear envelope couples the LINC complex to endoreplication.

Development (Cambridge, England) - 13 Dec 2020

Unnikannan C P, Reuveny Adriana, Grunberg Dvorah, Volk Talila

Abstract excerpt

DNA endoreplication has been implicated as a cell strategy for cell growth and in tissue injury. Here, we demonstrate that barrier-to-autointegration factor (BAF) represses endoreplication in Drosophila myofibers. We show that BAF localization at the nuclear envelope is eliminated in flies with mutations of the linker of nucleoskeleton and cytoskeleton (LINC) complex in which the LEM-domain protein Otefin is...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33168584
DOI: 10.1242/dev.191304
PMCID: PMC7758627

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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