Article
Species-specific restriction of apobec3-mediated hypermutation.
Journal of virology - 1 Feb 2008
Browne Edward P, Littman Dan R
Abstract excerpt
Apobec proteins are a family of cellular cytidine deaminases, among which several members have been shown to have potent antiviral properties. This antiviral activity is associated with the ability to cause hypermutation of retroviral cDNA. However, recent research has indicated that Apobec proteins are also able to inhibit retroviruses by other mechanisms that are independent of their deaminase activity. We have...
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