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Article

Differential Activity of APOBEC3F, APOBEC3G, and APOBEC3H in the Restriction of HIV-2.

Journal of molecular biology - 30 Jan 2022

Meissner Morgan E, Willkomm Nora A, Lucas Jamie, Arndt William G, Aitken Sarah F, Julik Emily J, Baliga Sunanda, Mansky Louis M

Abstract excerpt

Human immunodeficiency virus (HIV) mutagenesis is driven by a variety of internal and external sources, including the host APOBEC3 (apolipoprotein B mRNA editing enzyme catalytic polypetide-like 3; A3) family of mutagenesis factors, which catalyze G-to-A transition mutations during virus replication. HIV-2 replication is characterized by a relative lack of G-to-A mutations, suggesting infrequent mutagenesis by A3...

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Identifiers

PMID: 34774569
DOI: 10.1016/j.jmb.2021.167355
PMCID: PMC8752514

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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