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Article

The chemistry and biology of RNA editing by adenosine deaminases.

Nucleic acids symposium series (2004) - 1 Jan 2007

Beal Peter A, Maydanovych Olena, Pokharel Subhash

Abstract excerpt

Deamination of adenosines within mRNAs catalyzed by ADAR enzymes generates inosines at the corresponding nucleotide positions. Since inosine is decoded as guanosine, this reaction can lead to codon changes and the introduction of amino acids into a gene product not encoded in the gene. Translation of the different coding strands created by this process leads to protein structural diversity in the parent organism...

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Source

Identifiers

PMID: 18029597
DOI: 10.1093/nass/nrm042

Genes

ADAR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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