Article
Origins and evolution of ADAR-mediated RNA editing.
IUBMB life - 1 Jun 2009
Jin Yongfeng, Zhang Wenjing, Li Qi
Abstract excerpt
Adenosine deaminases acting on RNA (ADARs) convert adenosines to inosines in double-stranded RNA in animals. Identification of more ADAR targets and genome sequences of diverse eukaryotes present an opportunity to elucidate the origin and evolution of ADAR-mediated RNA editing. Comparative analysis of the adenosine deaminase family indicates that the first ADAR might have evolved from adenosine deaminases acting...
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