Article
High concordance between HIV-1 drug resistance genotypes generated from plasma and dried blood spots in antiretroviral-experienced patients.
AIDS (London, England) - 30 Nov 2007
Masciotra Silvina, Garrido Carolina, Youngpairoj Ae S, McNulty Amanda, Zahonero Natalia, Corral Angelica, Heneine Walid, de Mendoza Carmen, García-Lerma J Gerardo
Abstract excerpt
OBJECTIVE: Dried blood spots (DBS) are a convenient alternative to plasma for drug resistance testing in resource-limited settings. We investigated the correlation between resistance genotypes generated from DBS and plasma. DESIGN: Sixty DBS specimens from HIV-1 subtype B-infected antiretroviral-experienced (n = 58) and naive patients (n = 2) were tested. DBS were prepared using 50 mul blood and were stored with...
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