Article
HIV type-1 drug resistance testing on dried blood spots is feasible and reliable in patients who fail antiretroviral therapy in rural Tanzania.
Antiviral therapy - 1 Jan 2010
Johannessen Asgeir, Holberg-Petersen Mona, Lövgaarden Gunilla, Naman Ezra, Ormaasen Vidar, Matee Mecky I, Gundersen Svein G, Bruun Johan N
Abstract excerpt
BACKGROUND: HIV type-1 (HIV-1) drug resistance testing is rarely available in resource-limited settings because of high costs and stringent requirements for storage and transport of plasma. Dried blood spots (DBS) can be a convenient alternative to plasma, but the use of DBS needs validation under field conditions. We assessed the performance of DBS in genotypic resistance testing of patients who failed...
Topics
- Adolescent
- Adult
- Aged
- Antiretroviral Therapy, Highly Active
- Blood
- Child
- Child, Preschool
- Drug Resistance, Multiple, Viral
- Feasibility Studies
- Female