Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Comparison of Plasma, Dried Blood Spots, and Peripheral Blood Mononuclear Cells as Biosamples for HIV-1 Genotypic Drug Resistance in a Tertiary Care Center.

AIDS research and human retroviruses - 1 Feb 2026

Sabu Priyanka, Alex Diviya, Ramalingam Veena Vadhini, Demosthenes John Paul, Fletcher Gnanadurai John, Abraham Priya, Kannangai Rajesh

Abstract excerpt

The collection, storage, and transport of plasma, the ideal specimen for HIV-1 genotyping, is plagued by technical difficulties in resource-limited settings. We aimed to compare corresponding bio-samples for HIV-1 genotypic drug resistance testing. A total of 87 matched specimens of plasma, dried blood spots (DBS), and peripheral blood mononuclear cells (PBMCs) collected from 29 persons living with HIV (PLWH) in...

Topics

Humans
HIV-1
Leukocytes, Mononuclear
Drug Resistance, Viral
HIV Infections
Male
Tertiary Care Centers
Genotype
Female
Adult
Genotyping Techniques

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Plasma

Middle Aged

Specimen Handling

Viral Load

pol Gene Products, Human Immunodeficiency Virus

Source

Identifiers

PMID: 41467909
DOI: 10.1177/08892229251405793

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-41467909-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Comparison of Plasma, Dried Blood Spots, and Peripheral Blood Mononuclear Cells as Biosamples for HIV-1 Genotypic Drug Resistance in a Tertiary Care Center.PMID 41467909Read ↗

Dried blood spots for HIV-1 drug resistance and viral load testing: A review of current knowledge and WHO efforts for global HIV drug resistance surveillance.Semantic proximity Read ↗

Evaluation of dried blood spot specimens for HIV-1 drug-resistance testing using the Trugene HIV-1 genotyping assay.Semantic proximity Read ↗

High concordance between HIV-1 drug resistance genotypes generated from plasma and dried blood spots in antiretroviral-experienced patients.Semantic proximity Read ↗

Technologies for HIV-1 drug resistance testing: inventory and needs.Semantic proximity Read ↗

Genotypic testing for HIV-1 drug resistance using dried blood samples.Semantic proximity Read ↗

A validated in-house assay for HIV drug resistance mutation surveillance from dried blood spot specimens.Semantic proximity Read ↗

HIV type-1 drug resistance testing on dried blood spots is feasible and reliable in patients who fail antiretroviral therapy in rural Tanzania.Semantic proximity Read ↗

Dried Blood Spot Specimens Are a Suitable Alternative Sample Type for HIV-1 Viral Load Measurement and Drug Resistance Genotyping in Patients Receiving First-Line Antiretroviral TherapySemantic proximity Read ↗

Evaluation of in-house genotyping assay performance using dried blood spot specimens in the Global World Health Organization laboratory network.Semantic proximity Read ↗

Development and optimization of an internally controlled dried blood spot assay for surveillance of human immunodeficiency virus type-1 drug resistanceSemantic proximity Read ↗

HIV-1 drug resistance genotyping success rates and correlates of Dried-blood spots and plasma specimen genotyping failure in a resource-limited settingSemantic proximity Read ↗

Performance of plasma separation cards for HIV drug-resistance genotyping in a resource-limited setting: comparison with plasma samples.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.