Article
Genotypic testing for HIV-1 drug resistance using dried blood samples.
Archives of virology - 1 Jul 2010
Lira Rosalia, Valdez-Salazar Hilda, Vazquez-Rosales Guillermo, Rojas-Montes Othon, Ruiz-Tachiquin Martha, Torres-Ibarra Rocio, Cano-Dominguez Carlos, Maldonado-Rodríguez Angelica, Gomez Alejandro, Muñoz Onofre, Alvarez-Muñoz Ma-Teresa
Abstract excerpt
In third-world countries, dried blood samples (DBS) are a convenient alternative to plasma for monitoring viral load during HIV-1 therapy. In this study, we evaluated the feasibility of using DBS to perform HIV-1 drug resistance genotyping in a ViroSeq assay in which the protease and reverse transcriptase regions of the pol gene are analyzed. Fifty-seven antiretroviral genotypes from plasma samples were tested,...
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