Genotypic testing for HIV-1 drug resistance using dried blood samples.

doi:10.1007/s00705-010-0696-y

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Article

Genotypic testing for HIV-1 drug resistance using dried blood samples.

Archives of virology - 1 Jul 2010

Lira Rosalia, Valdez-Salazar Hilda, Vazquez-Rosales Guillermo, Rojas-Montes Othon, Ruiz-Tachiquin Martha, Torres-Ibarra Rocio, Cano-Dominguez Carlos, Maldonado-Rodríguez Angelica, Gomez Alejandro, Muñoz Onofre, Alvarez-Muñoz Ma-Teresa

Abstract excerpt

In third-world countries, dried blood samples (DBS) are a convenient alternative to plasma for monitoring viral load during HIV-1 therapy. In this study, we evaluated the feasibility of using DBS to perform HIV-1 drug resistance genotyping in a ViroSeq assay in which the protease and reverse transcriptase regions of the pol gene are analyzed. Fifty-seven antiretroviral genotypes from plasma samples were tested,...

Topics

Adult
Aged
Anti-HIV Agents
Drug Resistance, Multiple, Viral
Female
Genes, pol
Genotype
HIV Infections
HIV-1
Humans
Male
Middle Aged
RNA, Viral
Viral Load

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Viremia

Young Adult

Source

Open in PubMed

Identifiers

PMID: 20496089
DOI: 10.1007/s00705-010-0696-y

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