Article
HIV-1 resistance genotyping on dried serum spots.
AIDS (London, England) - 4 Mar 2005
Plantier Jean-Christophe, Dachraoui Raoudha, Lemée Véronique, Gueudin Marie, Borsa-Lebas Françoise, Caron François, Simon François
Abstract excerpt
OBJECTIVE: To assess the feasibility of HIV-1 group M resistance genotyping on dried serum spots, by testing samples from previously untreated patients, patients on treatment, and patients having stopped treatment, representing a wide genetic diversity panel. METHODS: Serum samples from 62 HIV-1-infected Caucasian and African patients, with viral load values from 715 copies/ml to more than 750,000 copies/ml, were...
Topics
- Antiretroviral Therapy, Highly Active
- Blood Specimen Collection
- Drug Monitoring
- Drug Resistance, Viral
- Feasibility Studies
- Genotype
- HIV Infections
- HIV-1
- Humans
- Phylogeny
- Reverse Transcriptase Polymerase Chain Reaction
