Article
A validated in-house assay for HIV drug resistance mutation surveillance from dried blood spot specimens.
Journal of virological methods - 1 Jun 2024
Neufeld Bronwyn, Munyuza Chantal, Reimer Alexandria, Capiña Rupert, Lee Emma R, Becker Marissa, Sandstrom Paul, Ji Hezhao, Cholette François
Abstract excerpt
Despite increasing scale-up of antiretroviral therapy (ART) coverage, challenges related to adherence and HIV drug resistance (HIVDR) remain. The high cost of HIVDR surveillance is a persistent challenge with implementation in resource-constrained settings. Dried blood spot (DBS) specimens have been demonstrated to be a feasible alternative to plasma or serum for HIVDR genotyping and are more suitable for lower...
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