Article
HIV-1 drug resistance testing from dried blood spots collected in rural Tanzania using the ViroSeq HIV-1 Genotyping System.
The Journal of antimicrobial chemotherapy - 1 Feb 2011
Johannessen Asgeir, Garrido Carolina, Zahonero Natalia, Naman Ezra, de Mendoza Carmen
Abstract excerpt
OBJECTIVES: To assess whether the commercial ViroSeq HIV-1 Genotyping System (Abbott Molecular, Des Plains, IL, USA) can be used in conjunction with dried blood spots (DBS) for clinical monitoring of drug resistance in patients who fail antiretroviral treatment (ART) in rural Tanzania. PATIENTS A...
Topics
- Anti-Retroviral Agents
- Drug Resistance, Viral
- Genotype
- HIV Infections
- HIV-1
- Humans
- Microbial Sensitivity Tests
- Molecular Diagnostic Techniques
- Mutation
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Sequence Analysis, RNA
- Specimen Handling
- Tanzania
- Treatment Failure
- Viral Load