Article
Morphometric abnormalities and hyperanxiety in genetically epileptic rats: a model of psychiatric comorbidity?
NeuroImage - 1 Apr 2009
Bouilleret Viviane, Hogan R Edward, Velakoulis Dennis, Salzberg Michael R, Wang Lei, Egan Gary F, O'Brien Terence J, Jones Nigel C
Abstract excerpt
BACKGROUND: Imaging studies of epilepsy patients with comorbid affective disturbance demonstrate morphometric changes in limbic brain regions implicated in psychiatric disease. Genetic Absence Epilepsy Rats from Strasbourg (GAERS), specifically bred for their epilepsy phenotype, also exhibit elevated anxiety-like behaviors suggesting a common causality. Here we examined whether relevant cerebral morphological...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
