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Article

Maternal care exerts disease‐modifying effects on genetic absence epilepsy and comorbid depression

31 Mar 2018

Abstract excerpt

WAG/Rij rats, a genetic animal model of absence epilepsy with comorbidity of depression, exhibit behavioral depression-like symptoms and spontaneous generalized spike-wave discharges (SWDs) in the EEG at the age of 6 to 8 months. The aim of the present study was to test the hypothesis that maternal care is an environmental factor which, along with genetic predisposition, may contribute to the expression of...

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PMID: 29604188
DOI: 10.1111/gbb.12477

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Maternal care exerts disease‐modifying effects on genetic absence epilepsy and comorbid depressionPMID 29604188Read ↗

The impact of early-life environment on absence epilepsy and neuropsychiatric comorbiditiesSemantic proximity Read ↗

Maternal care affects EEG properties of spike-wave seizures (including pre- and post ictal periods) in adult WAG/Rij rats with genetic predisposition to absence epilepsy.Semantic proximity Read ↗

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