Article
Evolution of MHC class I genes in higher primates.
Immunology and cell biology - 1 Aug 1996
Lienert K, Parham P
Abstract excerpt
The classical major histocompatibility complex (MHC) class I genes are conserved in higher primates. Motifs common to human, chimpanzee and gorilla alleles indicate that class I alleles diverged from ancestral sequences that existed before separation of these species. Analysis of native human populations such as Australian Aborigines and Amerindians shows that HLA-B is characterized by rapid generation of new...
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