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Article

Gene conversion: mechanisms, evolution and human disease.

Nature reviews. Genetics - 1 Oct 2007

Chen Jian-Min, Cooper David N, Chuzhanova Nadia, Férec Claude, Patrinos George P

Abstract excerpt

Gene conversion, one of the two mechanisms of homologous recombination, involves the unidirectional transfer of genetic material from a 'donor' sequence to a highly homologous 'acceptor'. Considerable progress has been made in understanding the molecular mechanisms that underlie gene conversion, its formative role in human genome evolution and its implications for human inherited disease. Here we assess current...

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PMID: 17846636
DOI: 10.1038/nrg2193

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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