The major histocompatibility complex and human evolution.

doi:10.1016/0168-9525(90)90042-5

Back to search

Article

The major histocompatibility complex and human evolution.

Trends in genetics : TIG - 1 Jan 1990

Klein J, Gutknecht J, Fischer N

Abstract excerpt

Many alleles at the human major histocompatibility complex (HLA) loci diverged before the divergence of humans and great apes from a common ancestor. This fact puts a lower limit on the size of the bottleneck in human evolution: the genus Homo must have been founded by no less than ten and probab...

Topics

Alleles
Biological Evolution
Humans
Major Histocompatibility Complex
Polymorphism, Genetic

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.